OESTROUS CYCLE MODULATING EFFECT OF HYDROMETHANOLIC EXTRACT OF AZADIRACHTA INDICA (A. JUSS) LEAVES IN WISTAR RATS

Authors

  • Ijeoma Chika Chibuogwu University of Abuja
  • Ahovi Abdullahumid University of Abuja
  • Agbonu Oluwa Adikpe University of Abuja
  • Thomas Barde University of Abuja
  • Samson Eneojo Abalaka University of Abuja

Keywords:

Azadirachta indica leaves, Oestrous cycle, Ovarian weight, Reproductive tract weight, Dioestrus

Abstract

The study aimed to explore the potential of Azadirachta indica leaves as a natural alternative for regulating the oestrous cycle in animal production. Eighteen mature Wistar rats were randomly assigned to three groups of six rats and treated per os with 0, 500, and 1000 mg/kg body weight of A. indica hydromethanolic leaf (AIHL) extract for 15 days. AIHL extract extended the average oestrous cycle period, increased dioestrus frequency, and decreased oestrus and metoestrus frequencies. Additionally, the ovarian and reproductive tract weights relative to body weight were significantly reduced (p < 0.05). The extract contained saponins, tannins, cabohydrates, terpenes, steroids, alkaloids, and flavonoids. Azadirachta indica leaves have the potential to modulate the mammalian oestrous cycle

Author Biographies

Ijeoma Chika Chibuogwu , University of Abuja

Department of Theriogenology

Ahovi Abdullahumid , University of Abuja

Department of Theriogenology

Agbonu Oluwa Adikpe , University of Abuja

Department of Veterinary Physiology and Biochemistry

Thomas Barde , University of Abuja

Department of Theriogenology

Samson Eneojo Abalaka, University of Abuja

Department of Veterinary Pathology

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Published

2025-03-20

How to Cite

Chibuogwu , I. C., Abdullahumid , A., Adikpe , A. O., Barde , T., & Abalaka, . S. E. (2025). OESTROUS CYCLE MODULATING EFFECT OF HYDROMETHANOLIC EXTRACT OF AZADIRACHTA INDICA (A. JUSS) LEAVES IN WISTAR RATS. Nigerian Journal of Animal Production, 265–267. Retrieved from https://mail.njap.org.ng/index.php/njap/article/view/8858

Issue

2025: Proceedings 2025

Section

Articles

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