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TY - JOUR AU - Amao, Emmanuel Ayodele AU - Amao, Oyetoun Dunmola AU - Mustapha , Khafayat Oluwadamilola AU - Ajibade , Fateemah Abisola AU - Adeyemi , Itunu Adesola PY - 2025/03/20 Y2 - 2026/07/29 TI - HAEMATOLOGICAL AND SERUM BIOCHEMICAL INDICES OF BROILER CHICKENS ADMINISTERED NEEM (Azadirachta indica) LEAF INFUSION AS A REPLACEMENT FOR ANTIBIOTICS JF - Nigerian Journal of Animal Production JA - NJAP VL - IS - SE - Articles DO - 10.51791/njap.vi.8620 UR - https://mail.njap.org.ng/index.php/njap/article/view/8620 SP - 480-483 AB - <p><em>Ninety-day-old broiler chicks were used in a six-week trial to evaluate the effect of neem (Azadirachta indica) leaf </em><em>infusion on haematological and serum biochemical profiles of broilers. The birds were randomly assigned into </em><em>five (5) groups in a completely randomized design. Each group was sub-divided into three (3) replicates of six (6) </em><em>birds each. The neem leaf infusion (NLI) was included at 0g/L,10g/L, 20g/L, 30g/L and 40g/L as a source of </em><em>antibiotics. Blood samples were collected from three birds in each treatment and evaluated for packed cell volume </em><em>(PCV), red blood cell (RBC), white blood cell (WBC) and white blood cell differentials at the end of the trial. Total </em><em>protein, albumin, globulin, Aspartate aminotransferase enzyme (AST), Alanine transaminase (ALT) and Alanine </em><em>phosphatase were evaluated for biochemical profile. Data collected were evaluated using one-way analysis of </em><em>variance. Packed cell volume was significantly (p&lt;0.05) affected in favour of birds on 40g/L NLI (33.00%), </em><em>haemoglobin and red blood cell were not significantly (p&gt;0.05) influenced by NLI. White blood cell was </em><em>significantly (p&lt;0.05) different across the treatments in favour of birds on 10g/L NLI (25.88 X10</em><em>9 </em><em>/ml). Total </em><em>protein, albumin and globulin were not significantly (p&lt;0.05) affected. Aspartate aminotransferase, ALT and ALP </em><em>were statistically (p&lt;0.05) different across the treatments with birds on 40g/L NLI having the highest values </em><em>(212.33, 36.30 and 239.35ul, respectively). The current findings suggest that NLI up to 40g/L has no deleterious </em><em>effect on haematological profile of broilers; nevertheless, biochemical indices revealed that NLI should not be </em><em>used above 20g/L to avert liver damage</em></p> ER -